When suffering can Gf drive a person over the edge

HH
Rabbi Nussun in Likutay Halachos (Yoreh Daya 2, Circumcision 5:20) discusses a person's breaking point, where the suffering instead of bringing him closer to HY will drive him away GF. This he asserts however, is primarily due to other people's interjection, preventing him from abnegating himself to HY and returning from the nullification with renewed Gd knowledge, and what even the worst natural calamities may the Merciful One save us cannot do, these people can do, if the person isn't Ironclad fast and strong in HY and His tzadik Na Nach Nachma Nachman Meuman.